Edit |   |
---|---|
Antigenic Specificity | Thioredoxin Reductase 1/TRXR1, Human |
Clone | AT30F1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases. |
Immunogen | Recombinant human TXNRD1 (161-647aa) purified from E. coli |
Other Names | GRIM 12, KDRF, KM 102 derived reductase like factor, MGC9145, Oxidoreductase, Thioredoxin reductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein, Thioredoxin reductase GRIM 12, TR, TR 1, TRXR 1, TXNR, TXNRD 1 |
Gene, Accession # | NCBI: NP_001087240, UniProt: Q16881 |
Catalog # | ATGA0451 |
Price | $170, $290 |
Order / More Info | Thioredoxin Reductase 1/TRXR1, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |