Edit |   |
---|---|
Antigenic Specificity | KLF7, Human |
Clone | AT3G3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein A purified |
Size | 50ul, 100ul |
Concentration | 1mg/ml (determined by BCA assay) |
Applications | ELISA,WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KLK7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation, survival and the development of nervous systems. and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 is binds specifically to an Ikaros core binding element that is crucial for in vivo NTRK1/TrkA enhancer function. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. |
Immunogen | Recombinant human KLF7 (1-302aa) purified from E. coli |
Other Names | Kruppel-like factor 7, uKLF |
Gene, Accession # | NCBI: NP_003700, UniProt: O75840 |
Catalog # | ATGA0256 |
Price | $170, $290 |
Order / More Info | KLF7, Human Antibody from NKMAX Co. Ltd. |
Product Specific References | n/a |