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Antigenic Specificity | GAPDH |
Clone | AT4E8 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 500ul, 1ml |
Concentration | 0.2mg/ml (determined by BCA assay) |
Applications | ELISA, WB, ICC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis in the cytoplasm, it is involved in the translational control of gene expression in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair. |
Immunogen | GAPDH from rabbit muscle |
Other Names | Glyceraldehyde-3-phosphate dehydrogenase isoform 1, Peptidyl-cysteine S-nitrosylase GAPDH, GAPD, G3PD |
Gene, Accession # | NCBI: NP_002037, UniProt: P04406 |
Catalog # | ATGA0592 |
Price | $102, $174 |
Order / More Info | GAPDH Antibody from NKMAX Co. Ltd. |
Product Specific References | Park SW, et al. Development of new tools to study membrane-anchored mammalian Atg8 proteins. (Autophagy. 2022){https://pubmed.ncbi.nlm.nih.gov/36250672/};;Hah YS, et al. β-Sitosterol Attenuates Dexamethasone-Induced Muscle Atrophy via Regulating FoxO1-Dependent Signaling in C2C12 Cell and Mice Model. (Nutrients. 2022){https://pubmed.ncbi.nlm.nih.gov/35889851/};;Hah YS, et al. Rutin Prevents Dexamethasone-Induced Muscle Loss in C2C12 Myotube and Mouse Model by Controlling FOXO3-Dependent Signaling. (Antioxidants. 2023){https://pubmed.ncbi.nlm.nih.gov/36978887/} |