GAPDH Antibody from NKMAX Co. Ltd.

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Antigenic SpecificityGAPDH
CloneAT4E8
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2b kappa
FormatProtein A purified
Size500ul, 1ml
Concentration0.2mg/ml (determined by BCA assay)
ApplicationsELISA, WB, ICC/IF
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DescriptionMultiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis in the cytoplasm, it is involved in the translational control of gene expression in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair.
ImmunogenGAPDH from rabbit muscle
Other NamesGlyceraldehyde-3-phosphate dehydrogenase isoform 1, Peptidyl-cysteine S-nitrosylase GAPDH, GAPD, G3PD
Gene, Accession #NCBI: NP_002037, UniProt: P04406
Catalog #ATGA0592
Price$102, $174
Order / More InfoGAPDH Antibody from NKMAX Co. Ltd.
Product Specific ReferencesPark SW, et al. Development of new tools to study membrane-anchored mammalian Atg8 proteins. (Autophagy. 2022){https://pubmed.ncbi.nlm.nih.gov/36250672/};;Hah YS, et al. β-Sitosterol Attenuates Dexamethasone-Induced Muscle Atrophy via Regulating FoxO1-Dependent Signaling in C2C12 Cell and Mice Model. (Nutrients. 2022){https://pubmed.ncbi.nlm.nih.gov/35889851/};;Hah YS, et al. Rutin Prevents Dexamethasone-Induced Muscle Loss in C2C12 Myotube and Mouse Model by Controlling FOXO3-Dependent Signaling. (Antioxidants. 2023){https://pubmed.ncbi.nlm.nih.gov/36978887/}
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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