Asc (Tyr-144) Antibody from PHOSPHOSOLUTIONS
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| Antigenic Specificity | Asc (Tyr-144) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, and rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | WB, ICC. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Asc (Tyr-144), Phosphospecific polyclonal antibody. This antibody was cross-adsorbed to unphosphorylated Asc (Tyr-144) peptide before affinity purification using phospho-Asc (Tyr-144) peptide. The antibody detects phosphorylated Asc (Tyr-144) in the inflammasome. In J774 macrophage cells primed with LPS and treated with nigericin, the antibody colocalized with an inflammasome marker, caspase-1 inhibitor (FAM-YVAD-FMK). In addition, the antibody detects a 20 kDa Asc protein in western blots of J774A.1 mouse macrophages treated with pervanadate. RRID: AB_2820240 |
| Immunogen | Asc (Tyr-144) phospho-peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-144 in mouse Asc. This peptide sequence is highly conserved in human and rat Asc. |
| Other Names | phospho- , phosphorylated Caspase, PYCARD, AIM, ASC, CARD5, TMS1 |
| Gene, Accession # | Pycard, UniProt: Q9EPB4 |
| Catalog # | AP5631 |
| Price | $329 |
| Order / More Info | Asc (Tyr-144) Antibody from PHOSPHOSOLUTIONS |
| Product Specific References | n/a |
PHOSPHOSOLUTIONS
PHOSPHOSOLUTIONS
Colorado Biosciences Park
12635 East Montview Blvd. #213
Aurora CO 80045-7337
P: 720-859-4050
P: 888-442-7100
F: 720-859-4052
info@phosphosolutions.com
http://www.phosphosolutions.com
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