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Antigenic Specificity | 4-Hydroxynonenal |
Clone | 12F7 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 ug |
Concentration | 1 mg/ml |
Applications | WB, ICC/IF, ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-4-Hydroxynonenal Mouse Monoclonal Antibody. 4-Hydroxy-2-nonenol (4-HNE) is an unsaturated aldehyde derived from lipid peroxidation. 4-HNE is an electrophile and reacts with protein nucleophiles such as cysteine, histine, and lysine (1). Low levels of 4-HNE promote cell survival via cellular antioxidant induction whereas higher levels lead to autophagy, apoptosis, and ultimately necrosis. 4-HNE has been linked to Alzheimer's disease, Parkinson's disease, cancer, cardiovascular diseases, diabetes, and liver disease. Specific for 4-Hydroxynonenal (4-HNE) modified proteins. Does not detect free 4-Hydroxynonenal. Does not cross-react with 4-Hydroxy-2-hexenal, Acrolein, Crotonaldehyde, Hexanoyl Lysine, Malondialdehyde, or Methylglyoxal modified proteins. |
Immunogen | Synthetic 4-Hydroxynonenal modified Keyhole Limpet Hemocyanin (KLH). |
Other Names | 4-Hydroxynonenal, 4-Hydroxy Nonenal (4-HNE), 4-Hydroxy Nonenal, 4-HNE, 4-hydroxy Hexenal, HNE, 4-hydroxy-2-nonenal |
Gene, Accession # | n/a |
Catalog # | 56612 |
Price | $441 |
Order / More Info | 4-Hydroxynonenal Antibody from QED BIOSCIENCE INC. |
Product Specific References | n/a |