Prekallikrein Heavy Chain Antibody from QED BIOSCIENCE INC.
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| Antigenic Specificity | Prekallikrein Heavy Chain |
| Clone | 13G11 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 200ug |
| Concentration | lot specific |
| Applications | WB, ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Prekallikrein Heavy Chain Mouse Monoclonal Antibody. This antibody recognizes two variants of prekallikrein in human plasma, 88kDa and 85kDa, and its activation products kallikrein, the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45kDa prekallikrein/kallikrein fragments. It also recognizes prekallikrein and its activation products in chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody is located on the prekallikrein/kallikrein hevy chain and is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by ~60- 80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein. |
| Immunogen | Purified human prekallikrein. |
| Other Names | EC 3.4.21.34, Fletcher factor, Kininogenin, Plasma prekallikrein, PKK [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] |
| Gene, Accession # | KLKB1, UniProt: P03952 |
| Catalog # | 19901 |
| Price | $635 |
| Order / More Info | Prekallikrein Heavy Chain Antibody from QED BIOSCIENCE INC. |
| Product Specific References | PubMed: 12090937 11557611 8856190 1455399 1711719 2481391 30791599 |
QED BIOSCIENCE INC.
QED BIOSCIENCE INC.
A part of Genovis, Inc.
10919 Technology Place, Suite C
San Diego CA 92127
P: (858) 675-2405
P: (800) 929-2114
F: (858) 592-1509
info@qedbio.com
http://www.qedbio.com
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