Mouse Alpha Synuclein Antibody from QED BIOSCIENCE INC.
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| Antigenic Specificity | Mouse Alpha Synuclein |
| Clone | 4F1 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 100 ug |
| Concentration | 1 mg/ml |
| Applications | WB, DB, IHC, ICC/IF, ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Mouse Alpha Synuclein Mouse Monoclonal Antibody. Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6). Binds multiple linear epitopes within human alpha synuclein: 21-70 aa, 61-90 aa, and 101-140 aa, determined using Dot blot and ELISA with corresponding peptides. Detects ~14 kDa band corresponding to Alpha synuclein. Band at ~40 kDa is a trimer. |
| Immunogen | Mouse alpha synuclein aggregate |
| Other Names | Alpha Synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, PARK1, PARK 1, alphaSYN, PARK 4, PARK4, Parkinson disease familial 1, Parkinson disease (autosomal dominant, Lewy body) 4, SYN |
| Gene, Accession # | SNCA, UniProt: O55042, Gene ID: 20617, Accession: NP_001035916.1 |
| Catalog # | 56627 |
| Price | $357 |
| Order / More Info | Mouse Alpha Synuclein Antibody from QED BIOSCIENCE INC. |
| Product Specific References | n/a |
QED BIOSCIENCE INC.
QED BIOSCIENCE INC.
A part of Genovis, Inc.
10919 Technology Place, Suite C
San Diego CA 92127
P: (858) 675-2405
P: (800) 929-2114
F: (858) 592-1509
info@qedbio.com
http://www.qedbio.com
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