Edit |   |
---|---|
Antigenic Specificity | ATM |
Clone | 2C1 |
Host Species | Mouse |
Reactive Species | human, mouse, rat, monkey |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100ug |
Concentration | lot specific |
Applications | WB, ICC/IF, IHC-P, FACS, IP, ELISA, ChIP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ATM Mouse Monoclonal Antibody. This antibody recognizes full-length ATM, a 370 kD nuclear phosphoprotein, which is involved in the autooal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigations. |
Immunogen | GST fusion protein expressed in E. coli corresponding to aa 2577- 3056 of full-length ATM. |
Other Names | EC 2.7.11.1, Ataxia telangiectasia mutated, A-T mutated |
Gene, Accession # | ATM, UniProt: Q13315, Gene ID: 472, Accession: NP_000042 |
Catalog # | 3310 |
Price | $503 |
Order / More Info | ATM Antibody from QED BIOSCIENCE INC. |
Product Specific References | PubMed: 8969240 |