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Antigenic Specificity | 4-Hydroxy-2-hexenal |
Clone | 6F10 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b |
Format | Protein G purified |
Size | 100 ug |
Concentration | 1 mg/ml |
Applications | WB, ICC/IF, ELISA, FACS, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-4-Hydroxy-2-hexenal Mouse Monoclonal Antibody. Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. 4-hydroxy-2-hexenal (4-HHE) is a major alpha,beta-unsaturated aldehyde product of n-3 PUFA oxidation resulting from lipid peroxidation. High levels of HHE are found in disease states (1). 4-HHE reacts with histidine residues to form Michael-addition type adducts. Specific for 4-Hydroxy-2-hexenal (4-HHE) and 4-Hydroxynonenal (4-HNE) modified proteins. Does not detect free 4-Hydroxy-2-hexenal (4-HHE) or 4-Hydroxynonenal (4-HNE). Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, Malondialdehyde, or Methylglyoxal modified proteins. |
Immunogen | Synthetic 4-Hydroxy-2-hexenal modified Keyhole Limpet Hemocyanin (KLH). |
Other Names | 4-Hydroxy-2-hexenal (4-HHE), 4-Hydroxy-2-hexenal, 4-HHE, MG, MG-modified protein, 4-Hydroxy-2-hexenal-modified , 4-Hydroxy-2-hexenal, 4-hydroxy Hexenal, HHE, 4-HHE |
Gene, Accession # | n/a |
Catalog # | 56611 |
Price | $441 |
Order / More Info | 4-Hydroxy-2-hexenal Antibody from QED BIOSCIENCE INC. |
Product Specific References | n/a |