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Antigenic Specificity | FOXP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-FOXP3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with FOXP3 from other sources has not been determined. FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. |
Immunogen | Anti- FOXP3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the C-terminus of human FOXP3. |
Other Names | FOXP3 Antibody, JM2, AIID, IPEX, PIDX, XPID, DIETER, JM2, Forkhead box protein P3, Scurfin |
Gene, Accession # | FOXP3, Gene ID: 50943, NCBI: NP_054728, UniProt: Q9BZS1 |
Catalog # | 600-401-BG9 |
Price | $475 |
Order / More Info | FOXP3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |