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Antigenic Specificity | EED |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-EED Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Four alternatively spliced transcript variants have been observed. The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin b7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication. |
Immunogen | Anti-EED antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the N-terminus of human EED. |
Other Names | EED Antibody, HEED, WAIT1, Polycomb protein EED, WD protein associating with integrin cytoplasmic tails 1, hEED |
Gene, Accession # | EED, Gene ID: 8726, NCBI: NP_003788, UniProt: O75530 |
Catalog # | 600-401-AZ1 |
Price | $475 |
Order / More Info | EED Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |