Edit |   |
---|---|
Antigenic Specificity | KLK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KLK4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. KLK4 antibody is human specific. At least three isoforms of KLK4 are known to exist. Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions (1). Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers (3). KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) (4). |
Immunogen | Anti-KLK4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the internal region of human KLK4. |
Other Names | KLK4 Antibody , ARM1, EMSP, PSTS, AI2A1, EMSP1, KLK-L1, PRSS17, kallikrein, Kallikrein-4, Enamel matrix serine proteinase 1 |
Gene, Accession # | KLK4, Gene ID: 9622, NCBI: NP_004908, UniProt: Q9Y5K2 |
Catalog # | 600-401-CF3 |
Price | $475 |
Order / More Info | KLK4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |