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Antigenic Specificity | FTO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-FTO Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with FTO from other sources has not been determined. Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist. |
Immunogen | Anti-FTO antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the N-terminus of human FTO. |
Other Names | FTO Antibody, ALKBH9, KIAA1752, Alpha-ketoglutarate-dependent dioxygenase FTO, Fat mass and obesity-associated protein |
Gene, Accession # | FTO, Gene ID: 79068, NCBI: NP_001073901.1, UniProt: Q9C0B1 |
Catalog # | 600-401-BH8 |
Price | $475 |
Order / More Info | FTO Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |