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Antigenic Specificity | RAB21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-RAB21 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is predicted to not cross-react with other Ras-related proteins. RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the a-tail of endocytosed integrin. |
Immunogen | Anti-RAB21 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the C-terminus of human RAB21. |
Other Names | RAB21 Antibody, KIAA0118, Ras-related protein Rab-21 |
Gene, Accession # | RAB21, Gene ID: 23011, NCBI: NP_055814, UniProt: Q9UL25 |
Catalog # | 600-401-DV7 |
Price | $475 |
Order / More Info | RAB21 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |