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Antigenic Specificity | VARP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-VARP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with VARP from other sources has not been determined. The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth. |
Immunogen | Anti-VARP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the N-terminus of human VARP. |
Other Names | VARP Antibody, VARP, PP12899, Ankyrin repeat domain-containing protein 27, VPS9 domain-containing protein |
Gene, Accession # | ANKRD27, Gene ID: 84079, NCBI: NP_115515.2, UniProt: Q96NW4 |
Catalog # | 600-401-FW0 |
Price | $475 |
Order / More Info | VARP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |