CARD10 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CARD10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-CARD10 Antibody is immunoaffinity purified. Cross reactivity with CARD10 from other sources has not been determined. Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kB. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the IkK complex, demonstrating its importance in the regulation of NF-kB transcription factor activation. |
| Immunogen | Anti-CARD10 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10. |
| Other Names | CARD10 Antibody, BIMP1, CARMA3, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3, Carma 3 |
| Gene, Accession # | CARD10, Gene ID: 29775, NCBI: AAK26165, UniProt: Q9BWT7 |
| Catalog # | 600-401-AB4 |
| Price | $475 |
| Order / More Info | CARD10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
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