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Antigenic Specificity | Neurofilament H |
Clone | NAP4 |
Host Species | Mouse |
Reactive Species | rat, bovine, chicken |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µL |
Concentration | n/a |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NF-H antibody is directed against Neurofilament H. The antibody is protein G purified from concentrated clarified cell culture supernate. Anti-NF-H recognizes phosphorylated NF-H KSP (lysine-serine-proline) type sequences. The antibody has been directly tested for reactivity in chicken and a wide variety of mammals. In some species there is some cross-reactivity with the related phosphorylated KSP sequences found in the related neurofilament subunit NF-M. It recognizes neurofilaments in frozen sections in tissue culture and in formalin fixed sections. NF-H antibody detects Neurofilament H. Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease. Anti-ANeurofilament H antibody is ideal for investigators involved in Cell Signaling and Neuroscience research. |
Immunogen | Anti-NF-H Antibody was produced by repeated immunizations with purified native bovine NF-H. |
Other Names | mouse anti-Neurofilament H Antibody, Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein |
Gene, Accession # | NEFH, Gene ID: 4744, NCBI: DAA20547.1, UniProt: P12036 |
Catalog # | 900-301-D82 |
Price | $475 |
Order / More Info | Neurofilament H Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |