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Antigenic Specificity | OCLN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-OCLN Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with OCLN from other sources has not been determined. Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist. |
Immunogen | Anti-OCLN antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the C-terminus of human OCLN. |
Other Names | OCLN Antibody, BLCPMG, Occludin |
Gene, Accession # | OCLN, Gene ID: 4950, NCBI: AAH29886, UniProt: Q16625 |
Catalog # | 600-401-DG2 |
Price | $475 |
Order / More Info | OCLN Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |