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Antigenic Specificity | BASSOON |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Bassoon Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Bassoon from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Other species not yet tested. Cross-reactivity with Bassoon from other sources has not been determined. Neuroscience research. Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntingtin, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to colocalize with GABA (A) and glutamate (GluR1) receptors. |
Immunogen | Bassoon Antibody was produced from whole rabbit serum prepared by repeated immunizations with a N-terminal his-tagged fusion protein. |
Other Names | BSN, ZNF231, Neuronal double zine finger protein, protein bassoon |
Gene, Accession # | BSN, Gene ID: 8927, NCBI: NP_003449.2, UniProt: Q9UPA5 |
Catalog # | 600-401-E93 |
Price | $445 |
Order / More Info | BASSOON Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |