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Antigenic Specificity | TRIM24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TRIM24 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of TRIM24 are known to exist. TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC). |
Immunogen | Anti-TRIM24 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the internal region of human TRIM24. |
Other Names | TRIM24 Antibody, PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA, Transcription intermediary factor 1-alpha, E3 ubiquitin-protein ligase TRIM24, TIF1-alpha |
Gene, Accession # | TRIM24, Gene ID: 8805, NCBI: NP_003843.3, UniProt: O15164 |
Catalog # | 600-401-FN9 |
Price | $475 |
Order / More Info | TRIM24 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |