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Antigenic Specificity | GRIK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Grik2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Grik2 from other sources has not been determined. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik2, also known as glutamate receptor 6, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Recent reports have suggested that defects in the Grik2 protein may be associated with autosomal recessive mental retardation and possibly other neurological disorders such as schizophrenia. Numerous isoforms of Grik2 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow. This Grik2 antibody may exhibit some cross-reactivity to Grik3. |
Immunogen | Anti-Grik2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide near the C-terminus of the human Grik2. |
Other Names | Grik2 Antibody, EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2, Glutamate receptor ionotropic, kainate 2, Excitatory amino acid receptor 4 |
Gene, Accession # | GRIK2, Gene ID: 2898, NCBI: NP_001159719.1, UniProt: Q13002 |
Catalog # | 600-401-BN6 |
Price | $475 |
Order / More Info | GRIK2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |