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Antigenic Specificity | MLIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MLIP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of MLIP are known to exist. The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies |
Immunogen | Anti-MLIP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human MLIP. |
Other Names | MLIP Antibody, C6orf142, C6orf142, Muscular LMNA-interacting protein, Muscular-enriched A-type laminin-interacting protein |
Gene, Accession # | MLIP, Gene ID: 90523, NCBI: NP_612636, UniProt: Q5VWP3 |
Catalog # | 600-401-CU8 |
Price | $475 |
Order / More Info | MLIP Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |