NOD2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NOD2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NOD2 Antibody is immunoaffinity chromatography purified IgG. A BLAST analysis was used to suggest cross-reactivity with NOD2 with Human based on 100% homology with the immunizing sequence. Cross-reactivity with NOD2 from other sources has not been determined. Antibody has no cross reaction with NOD1. NOD2 Antibody detects human NOD2. Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-kappaB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease. Anti-NOD2 antibodies are ideal for investigators involved in NFkappaB and Cytokines and Growth factor research. |
| Immunogen | NOD2 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to amino acids at the c-terminus of human NOD2. |
| Other Names | Nucleotide-binding oligomerization domain-containing protein 2, Caspase recruitment domain-containing protein 15, Inflammatory bowel disease protein 1, NOD2, CARD15, IBD1 |
| Gene, Accession # | NOD2, Gene ID: 64127, NCBI: NP_001280486.1, UniProt: Q9HC29 |
| Catalog # | 600-401-H05 |
| Price | $475 |
| Order / More Info | NOD2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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