Serotonin Receptor 3A Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySerotonin Receptor 3A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein G purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsWestern Blot
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DescriptionAnti-Serotonin Receptor 3A Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 3A from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Serotonin Receptor 3A from other sources has not been determined. Anti-Serotonin Receptor 3A Antibody detect rat Serotonin Recepto 3A. Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. A 5-HT3 receptor is distinguished from other 5-HT receptors by its structure and function. 5-HT3 receptors span the membrane only four times and are ligand-gated, cation-selective ion channels that mediate neuronal excitation and exocytotic release of neurotransmitters within the peripheral and central nervous systems. Functional studies done on isolated tissues have revealed heterogeneity of this receptor. The human 5-HT3 Receptor Alpha subunits cDNA contains an open reading frame of 1434 base pairs predicting a 23-residue signal peptide and a mature receptor subunit of 455 amino acids. The human subunit exhibits 85% and 84% amino acid sequence identity to the mouse and rat receptors, respectively. 5-HT3 Receptor polyclonal antibody shows immunoreactivity in the forebrain (olfactory regions, hippocampal formation and amygdala), sensory and motor nuclei of brainstem and spinal cord. Anti-Serotonin Receptor 3A Antibody is ideal for investigators involved neurobiology research.
ImmunogenSerotonin Receptor 3A Antibody was produced from whole rabbit serum prepared by repeated immunizations with a mixture of synthetic peptides corresponding to two internal amino acid sequences in rat 5-HT1BR protein.
Other Names5-HT3
Gene, Accession #Htr3a, Gene ID: 79246, NCBI: NP_077370.2, UniProt: Q62999
Catalog #200-401-I12
Price$525
Order / More InfoSerotonin Receptor 3A Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

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