SNCA Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySNCA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-SNCA antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. SNCA antibody is human, mouse and rat reactive. At least three isoforms of SNCA are known to exist. Alpha-Synuclein (SNCA) is a hallmark of Alzheimer's disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson's disease (4,5).
ImmunogenAnti-SNCA antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human SNCA.
Other NamesSNCA Antibody, PD1, NACP, PARK1, PARK4, Alpha-synuclein, Non-A beta component of AD amyloid
Gene, Accession #SNCA, Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840
Catalog #600-401-ER8
Price$475
Order / More InfoSNCA Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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