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Antigenic Specificity | TIP5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | Neat |
Applications | Chip, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TIP5 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with TIP5 from other species not tested. TIP 5 is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain. Anti-TIP5 Antibody is ideal for research in Gene Expression. |
Immunogen | Anti-TIP5 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human TIP5. |
Other Names | Bromodomain adjacent to zinc finger domain protein 2A, Transcription termination factor I-interacting protein 5, TTF-I-interacting protein 5, hWALp3 |
Gene, Accession # | BAZ2A, Gene ID: 11176, NCBI: NP_038477.2, UniProt: Q9UIF9 |
Catalog # | 100-401-V86 |
Price | $475 |
Order / More Info | TIP5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |