NALP2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NALP2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NALP2 Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with NALP2 from other sources has not been determined. NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1b-processing activity and is thought to function as a modulator of NF-kB and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2. |
| Immunogen | Anti-NALP2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 12 amino acids near the C-terminus of human NALP2. |
| Other Names | NALP2 Antibody, NBS1, PAN1, NALP2, PYPAF2, CLR19.9, NBS1, NACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1 |
| Gene, Accession # | NLRP2, Gene ID: 55655, NCBI: NP_060322, UniProt: Q9NX02 |
| Catalog # | 200-401-CY1 |
| Price | $475 |
| Order / More Info | NALP2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
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