Edit |   |
---|---|
Antigenic Specificity | WNV Core |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-WNV Core Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with WNV Core from other sources has not been determined. West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation. |
Immunogen | Anti-WNV Core antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to 15 amino acids near the N-terminus of the WNV Core protein. |
Other Names | WNV Core Antibody , Genome polyprotein, Core protein, NS1 |
Gene, Accession # | WNVgp1, Gene ID: 912267, NCBI: NP_776012, UniProt: P06935 |
Catalog # | 600-401-FZ4 |
Price | $475 |
Order / More Info | WNV Core Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |