BIM Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityBIM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-Bim Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bim from other sources has not been determined. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
ImmunogenAnti-Bim antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 20 amino acids near the amino terminus of human BIM. The immunogen is located within the first 50 amino acids of BIM.
Other NamesBim Antibody, BAM, BIM, BOD, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-L-11, BCL2L11
Gene, Accession #BCL2L11, Gene ID: 10018, NCBI: NP_619527, UniProt: O43521
Catalog #600-401-Z69
Price$475
Order / More InfoBIM Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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