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Antigenic Specificity | BIM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Bim Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bim from other sources has not been determined. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines. |
Immunogen | Anti-Bim antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 20 amino acids near the amino terminus of human BIM. The immunogen is located within the first 50 amino acids of BIM. |
Other Names | Bim Antibody, BAM, BIM, BOD, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-L-11, BCL2L11 |
Gene, Accession # | BCL2L11, Gene ID: 10018, NCBI: NP_619527, UniProt: O43521 |
Catalog # | 600-401-Z69 |
Price | $475 |
Order / More Info | BIM Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |