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Antigenic Specificity | NUP160 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-NUP160 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NUP160 from other sources has not been determined. The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist. |
Immunogen | Anti-NUP160 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the C-terminus of human NUP160. |
Other Names | NUP160 Antibody, KIAA0197, NUP120, Nuclear pore complex protein Nup160, 160 kDa nucleoporin |
Gene, Accession # | NUP160, Gene ID: 23279, NCBI: EAW67881, UniProt: Q12769 |
Catalog # | 600-401-DF5 |
Price | $475 |
Order / More Info | NUP160 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |