GLE1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | GLE1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Gle1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Gle1 from other sources has not been determined. The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist. |
| Immunogen | Anti-GLE1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the internal region of human Gle1. |
| Other Names | Gle1 Antibody, LCCS, GLE1L, LCCS1, hGLE1, Nucleoporin GLE1, GLE1-like protein |
| Gene, Accession # | GLE1, Gene ID: 2733, NCBI: NP_001003722, UniProt: Q53GS7 |
| Catalog # | 600-401-BL3 |
| Price | $475 |
| Order / More Info | GLE1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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