MEK1 phospho T292 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | MEK1 phospho T292 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MEK1 pT292 antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Expect reactivity with the following species based on sequence homology:bovine, canine, human, mouse, non-human primates and rat. Cross reactivity with MEK1 pT292 from other species has not been determined. MEK1 pT292 antibody detects MEK1 phosphorylated at Thr292. MEK 1 (MAP kinase kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. Conversely, there also appears to be a feedback phosphorylation of MEK 1 by MAP kinase. The sites on MEK 1 that are phosphorylated by MAP kinase are Thr292 and Thr386. Therefore, MEK1 pT292 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research. |
| Immunogen | Anti-MEK1 pT292 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Thr292 conjugated to KLH. |
| Other Names | Dual specificity mitogen-activated protein kinase kinase 1, MAPKK 1, ERK activator kinase 1,MAPK/ERK kinase 1 |
| Gene, Accession # | MAP2K1, Gene ID: 5604, NCBI: AAI39730.1, UniProt: Q02750 |
| Catalog # | 600-401-D72 |
| Price | $475 |
| Order / More Info | MEK1 phospho T292 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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