IPO-38 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityIPO-38
CloneIPO-38
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgM kappa
FormatProtein A purified
Size100 µg
Concentration1.0 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionAnti-IPO-38 monoclonal antibody was purified by Protein A chromatography. This antigen was detected after 12h of PHA-induced activation in the early G1 phase but absent in non-stimulated lymphocytes. Cross reactivity is likely to occur with mouse and rat. Reactivity with other sources has not been determined. The specificity of mAb IPO-38 was demonstrated in different human and murine lymphoid and non-lymphoid cell lines. It does not react with mononuclear cells and granulocytes of healthy donors but does react with nuclei of blood cells of patients with different forms of leukemia and with cells from lymph nodes of patients with Hodgkin's disease and non-hodgkin's lymphoma. Also a positive reaction in nuclei of breast and colorectal tumor cells was demonstrated. IPO-38 may be a good marker of cellular proliferation during monitoring of tumor progression.
ImmunogenA BALB/c mouse was immunized with spleen cells of a human patient with hairy cell leukemia.
Other Namesmouse anti-IPO38 antibody, mouse anti-HMGN1 antibody, mouse anti-HMG14 antibody, Non-histone chromosomal protein HMG-14 antibody, High-mobility group nucleosome-binding domain-containing protein 1 antibody
Gene, Accession #Hmgn1, Gene ID: 15312, NCBI: NP_032277.3, UniProt: P18608
Catalog #200-301-278
Price$485
Order / More InfoIPO-38 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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