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Antigenic Specificity | IPO-38 |
Clone | IPO-38 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM kappa |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IPO-38 monoclonal antibody was purified by Protein A chromatography. This antigen was detected after 12h of PHA-induced activation in the early G1 phase but absent in non-stimulated lymphocytes. Cross reactivity is likely to occur with mouse and rat. Reactivity with other sources has not been determined. The specificity of mAb IPO-38 was demonstrated in different human and murine lymphoid and non-lymphoid cell lines. It does not react with mononuclear cells and granulocytes of healthy donors but does react with nuclei of blood cells of patients with different forms of leukemia and with cells from lymph nodes of patients with Hodgkin's disease and non-hodgkin's lymphoma. Also a positive reaction in nuclei of breast and colorectal tumor cells was demonstrated. IPO-38 may be a good marker of cellular proliferation during monitoring of tumor progression. |
Immunogen | A BALB/c mouse was immunized with spleen cells of a human patient with hairy cell leukemia. |
Other Names | mouse anti-IPO38 antibody, mouse anti-HMGN1 antibody, mouse anti-HMG14 antibody, Non-histone chromosomal protein HMG-14 antibody, High-mobility group nucleosome-binding domain-containing protein 1 antibody |
Gene, Accession # | Hmgn1, Gene ID: 15312, NCBI: NP_032277.3, UniProt: P18608 |
Catalog # | 200-301-278 |
Price | $485 |
Order / More Info | IPO-38 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |