Edit |   |
---|---|
Antigenic Specificity | LAMTOR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-LAMTOR1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. LAMTOR1 antibody is human, mouse and rat specific. LAMTOR1 antibody is predicted to not cross-react with other LAMTOR family proteins. LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes (1). The mTORC1 kinase complex is a critical component in the regulation of cell growth (2). As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids (3). LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes (4). |
Immunogen | Anti- LAMTOR1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the N-terminus of human LAMTOR1 |
Other Names | LAMTOR1 Antibody, p18, PDRO, C11orf59, p27RF-Rho, Ragulator1, PP7157, Ragulator complex protein LAMTOR1, Lipid raft adaptor protein p18 |
Gene, Accession # | LAMTOR1, Gene ID: 55004, NCBI: NP_060377, UniProt: Q6IAA8 |
Catalog # | 600-401-CH3 |
Price | $475 |
Order / More Info | LAMTOR1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |