Edit |   |
---|---|
Antigenic Specificity | IL-8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cat |
Isotype | n/a |
Format | Protein A purified |
Size | 25 µL |
Concentration | 1.13 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was protein A purified from monospecific antiserum by chromatography. This antibody is specific for cat IL-8 protein. A BLAST analysis was used to suggest cross-reactivity with IL-8 from cat sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-8 from other sources has not been determined. IL-8 (CXCL8) is a small cytokine belonging to the chemokine CXC subfamily. There have been 17 different CXC chemokines described in mammals. The members of the CXC chemokine subfamily have been subdivided into two categories - those with a specific amino acid sequence of glutamic acid-leucine-arginine (ELR) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. IL-8 is an ELR-positive CXC chemokine. The primary function of IL-8 is to recruit neutrophils to the site of inflammation. It also activates neutrophil functions and promotes angiogenesis. Anti-IL-8 antibody is ideal for investigators involved in Cancer, Cardiovascular and Immunology research. |
Immunogen | This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to 79 amino acids of mature cat IL-8 protein. |
Other Names | rabbit anti-IL-8 antibody, IL8, rabbit anti-Interleukin-8 antibody, C-X-C motif chemokine 8, CXCL8, Chemokine (C-X-C motif) ligand 8 |
Gene, Accession # | CXCL8, Gene ID: 493836, NCBI: NP_001009281.1, UniProt: Q9XSX5 |
Catalog # | 202-401-311S |
Price | $125 |
Order / More Info | IL-8 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |