MEK1/2 phosphoS218/pS222 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | MEK1/2 phosphoS218/pS222 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | Titrated value sufficient to run approximately 10 mini blots. |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-MEK 1/2 pS218/pS222 antibodies is directed against MEK protein phosphorylated at pS218 and pS222. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Expect reactivity with the following species based on sequence homology: bovine, canine, chicken, non-human primate, rat, Xenopus, and zebra fish. Cross reactivity with MEK 1/2 pS218/pS222 from other species has not been determined. MEK 1/2 pS218/pS222 antibodies detect MEK 1. MAP Kinase Kinase, also known as MKK or MEK, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. Therefore, MEK1/2 pS218/pS222 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research |
| Immunogen | Anti-MEK 1/2 pS218/pS222 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser218/222 conjugated to KLH. |
| Other Names | Dual specificity mitogen-activated protein kinase kinase 1, MAPKK 1, ERK activator kinase 1,MAPK/ERK kinase 1 |
| Gene, Accession # | MAP2K1/MAP2K2, Gene ID: 5604, NCBI: NP_002746.1, UniProt: Q02750 |
| Catalog # | 600-401-C84 |
| Price | $475 |
| Order / More Info | MEK1/2 phosphoS218/pS222 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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