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Antigenic Specificity | c-erbB2 |
Clone | SP3 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | supernatant |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-erbB2 Antibody is clarified tissue culture supernate. The antibody is specific for human c-erbB2 protein. Cross-reactivity with c-erbB2 protein from other sources has not been determined. The ERBB2 gene encodes a member of the tyrosine protein kinase superfamily that is an essential component of a neuregulin-receptor complex called c-erbB2 (also known as Receptor tyrosine-protein kinase erbB-2, p185erbB2, C-erbB-2, NEU proto-oncogene, tyrosine kinase-type cell surface receptor HER2, MLN 19 and CD340), although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. C-erbB2 is not activated by EGF, TGF-alpha and amphiregulin. Defects in ERBB2 are associated with gastric cancer, familial glioma of brain (glioblastoma multiforme), ovarian cancer and lung cancer (adenocarcinoma of lung). c-erbB2 antibody is ideal for Cancer and Signal Transduction research. |
Immunogen | erbB2 monoclonal antibody was produced by repeated immunizations with a recombinant protein corresponding to amino acid residues encoding the extracellular domain of human c-erbB2 protein. The hybridoma was produced by fusing New Zealand White rabbit splenocytes and myeloma cells using conventional technology. |
Other Names | rabbit anti-c-erbB2 Antibody, Receptor tyrosine-protein kinase erbB-2, p185erbB2, C-erbB-2, NEU proto-oncogene, tyrosine kinase-type cell surface receptor HER2, MLN 19, CD340 |
Gene, Accession # | ERBB2, Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626 |
Catalog # | 900-C01-B37 |
Price | $449 |
Order / More Info | c-erbB2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |