Calnexin-CT Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Calnexin-CT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, dog |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 200 µg |
| Concentration | 1mg/mL |
| Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Calnexin -CT Antibody was purified by Protein A chromatography. A BLAST analysis was used to suggest cross-reactivity with Calnexin -CT from Human, Monkey, Mouse, Rat, Bovine, Chicken (weak), Dog, Guinea pig, Hamster, Pig, Quail, Rabbit, Sheep, Drosophila (weak), and Xenopus (weak) based on 100% homology with the immunizing sequence. Cross-reactivity with Calnexin -CT from other sources has not been determined. Cell Signaling and Organelle Marker research. Calnexin, an abundant ~90kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90. It consists of a large 50kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail. Unlike its ER counterparts which have a KDEL sequence on their C-terminus to ensure ER retention, calnexin has positively charged cytosolic residues that do the same thing. Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multi-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglycosylated glycans. Calnexin has also been shown to associate with the major histocompatibility complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin. |
| Immunogen | Calnexin-CT Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of dog calnexin. Identical to human, mouse and rat calnexin sequences over these residues. |
| Other Names | CANX, CNX, IP90, P90, Calnexin, pp90 |
| Gene, Accession # | CANX, Gene ID: 403908, NCBI: NP_001003232.1, UniProt: P24643 |
| Catalog # | 200-401-E97 |
| Price | $475 |
| Order / More Info | Calnexin-CT Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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