Bim EL Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityBim EL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, IF Microscopy, Western Blot
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DescriptionAnti-Bim EL Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist; this antibody only detects the Bim EL isoform. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
ImmunogenAnti-Bim EL antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 15 amino acids near the N-terminus of human Bim.
Other NamesBim EL Antibody, BAM, BIM, BOD, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-L-11
Gene, Accession #BCL2L11, Gene ID: 10018, NCBI: NP_619527, UniProt: O43521
Catalog #600-401-Z73
Price$475
Order / More InfoBim EL Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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