PERP Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityPERP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsWestern Blot
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DescriptionAnti-PERP Antibody is affinity chromatography purified via peptide column. A BLAST analysis was used to suggest cross-reactivity with PERP with Human based on 100% homology with the immunizing sequence. Cross-reactivity with PERP from other sources has not been determined. PERP antibody detects human PERP. The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family. Anti-PERP antibodies are ideal for investigators involved in Apoptosis research.
ImmunogenPERP Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to amino acids near the c-terminus of human PERP, which differ from the mouse sequence by three amino acids.
Other Namesp53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW, PERP, KCP1, KRTCAP1, PIGPC1, THW
Gene, Accession #PERP, Gene ID: 94241, UniProt: Q96A56
Catalog #200-401-H10
Price$475
Order / More InfoPERP Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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