Tryptophan Hydroxylase phospho S260 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-Tryptophan Hydroxylase phospho S260 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Tryptophan Hydroxylase phospho S260 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Tryptophan Hydroxylase pS260 antibody is directed against rat Tryptophan Hydroxylase. Tryptophan Hydroxylase pS260 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, chicken, mouse and zebra fish. Tryptophan Hydroxylase pS260 antibody detects Tryptophan Hydroxylase, which catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II). CaM K II phosphorylates Ser260 which lies within the regulatory domain of TPH. Anti-THPpS260 Antibody is ideal for investigators involved in Cell Signaling, and Neuroscience research. |
| Immunogen | Anti-Tryptophan Hydroxylase pS260 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser260 of Tryptophan Hydroxylase. |
| Other Names | Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH |
| Gene, Accession # | Tph1, Gene ID: 24848, UniProt: P09810 |
| Catalog # | 600-401-E49 |
| Price | $475 |
| Order / More Info | Tryptophan Hydroxylase phospho S260 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies