Xin Actin-binding Repeat-containing Protein 1 Phospho S295 (XIRP1) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Xin Actin-binding Repeat-containing Protein 1 Phospho S295 (XIRP1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | immunoaffinity purified, no preservative |
| Size | 100 µL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Phospho-Ser295 Xin Actin-Binding Repeat Containing Protein 1 Antibody is directed against Xin Actin-Binding Repeat Containing Protein 1 phosphorylated at S295. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated Xin Actin-Binding Repeat Containing Protein 1. Minimal reactivity occurs against non-phosphorylated Xin Actin-Binding Repeat Containing Protein 1. Reactivity against Xin Actin-Binding Repeat Containing Protein 1 occurs from mouse sources. However, reactivity is also expected against canine, human, non-human primate, and rat based on 100% sequence homology. XIRP1 is a member of the Xin family of proteins, containing 16 Xin repeats. The intercalated disk protein Xin protects actin filaments from depolymerization, and is able to bundle actin filaments to interact with β-catenin, which is thought to stabilize actin-based cytoskeletons. The evolutionary emergence of the Xin paralogs may have played a key role in the development of heart chambers with complete endothelial and myocardial layers. Loss of mXinα (mouse Xin homolog) results in cardiac hypertrophy and cardiomyopathy. Phosphorylation of Ser295 is thought to play a key role in XIRP signaling. Xin Actin-Binding Repeat Containing Protein 1 pS295 Antibody is ideal for researchers interested in cell cycle research. |
| Immunogen | Anti-Phospho-Ser295 Xin Actin-Binding Repeat Containing Protein 1 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser295 of mouse Xin Actin-binding Repeat-containing Protein 1 conjugated to KLH. |
| Other Names | XIRP1, Cardiomyopathy-associated protein 1, Xin actin-binding repeat-containing protein 1, Xirp1, Cmya1, Xin |
| Gene, Accession # | Xirp1, Gene ID: 22437, NCBI: O70373, UniProt: O70373 |
| Catalog # | 600-401-X37 |
| Price | $475 |
| Order / More Info | Xin Actin-binding Repeat-containing Protein 1 Phospho S295 (XIRP1) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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