IRAK-M Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | IRAK-M |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-IRAK-M Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with IRAK-M with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with IRAK-M from other sources has not been determined. Antibody has no cross to IRAK or IRAK2. IRAK-M (Interleukin-1 receptor-associated kinase M). Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induce cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). Through IL-1/Toll receptors, IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-kB (1,2); a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M (3). IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-kB activation. Members of the IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS. Anti-IRAK-M is ideal for investigators involved in Cytokines and Growth Factor research. |
| Immunogen | IRAK-M Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids from the c-terminus of human IRAK-M. |
| Other Names | IL 1 receptor associated kinase M antibody, Interleukin 1 Receptor Associated Kinase 3 antibody, Interleukin 1 Receptor Associated Kinase M antibody, IRAK 3 antibody, IRAK M antibody, IRAK3 antibody |
| Gene, Accession # | IRAK3, Gene ID: 73914, NCBI: 5225378, UniProt: Q9Y616 |
| Catalog # | 600-401-954 |
| Price | $475 |
| Order / More Info | IRAK-M Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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