Calcitonin Gene Related Peptide (CGRP) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Calcitonin Gene Related Peptide (CGRP) |
| Clone | 4901 |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 100 µL |
| Concentration | Titrated value sufficient to run approximately 10 mini blots. |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-CGRP Monoclonal Antibody is directed against rat CGRP protein. The antibody was purified from concentrated tissue culture supernate by Protein G chromatography. This antibody is specific for human and rat CGRP protein. A BLAST analysis was used to suggest cross-reactivity with CGRP from most mammalian sources based on very high homology with the immunizing sequence. Calcitonin Gene Related Peptide antibody also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP). CGRP antibody recognizes Calcitonin Gene Related Peptide or CGRP which is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known. CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches. CGRP antibodies have been used successfully in immunoneutralization. Anti-CGRP antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
| Immunogen | Anti-CGRP Monoclonal Antibody was produced by repeated immunizations with purified rat alpha-CGRP. |
| Other Names | Alpha-type CGRP, Calcitonin gene-related peptide I, Calcitonin gene-related peptide 1, CGRP-I, Calca, Calc |
| Gene, Accession # | Calca, Gene ID: 24241, NCBI: NP_001029128.1, UniProt: P01256 |
| Catalog # | 200-301-D15 |
| Price | $485 |
| Order / More Info | Calcitonin Gene Related Peptide (CGRP) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 29691410 // 33523928 // 34077727 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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