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Antigenic Specificity | CD45 |
Clone | 30-F11 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b kappa |
Format | phycoerythrin (RPE) conjugate |
Size | 100 µg |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phycoerythrin conjugated CD45 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD45. Cross-reactivity with CD45 from other sources has not been tested. Anti-CD45 is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets. |
Immunogen | Anti-CD45 Antibody (Monoclonal) was produced by repeated immunizations with CD45 antigen. |
Other Names | Receptor-type tyrosine-protein phosphatase C, , ukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 |
Gene, Accession # | Ptprc UniProt: P06800 |
Catalog # | 200-508-N83 |
Price | $155 |
Order / More Info | CD45 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |