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Antigenic Specificity | Spectrin (alpha and beta) |
Clone | SB-SP1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Spectrin antibody was purified from mouse ascites by protein A chromatography. This product reacts with human. Cross reactivity with Spectrin from other sources has not been determined. Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5. This antibody is suitable for researchers interested in cytoskeleton and transcription factor research. |
Immunogen | Spectrin(alpha and beta) antibody was produced in mice by repeated immunizations with human erythrocyte spectrin. |
Other Names | EL2, HPP, HS3, SPH3, SPTA, SPTA1, EL3, HS2, SPH2, HSPTB1, Erythroid alpha-spectrin, Spectrin alpha chain erythrocytic 1, Spectrin beta chain erythrocytic, Beta-I spectrin, SPTB, SPTB1 |
Gene, Accession # | SPTA1/SPTB, Gene ID: 6708, NCBI: NP_003117.2, UniProt: P02549 |
Catalog # | 200-301-P46 |
Price | $485 |
Order / More Info | Spectrin (alpha and beta) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |