RIG-1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | RIG-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | DEAE purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-RIG-1 Antibody is DEAE purified. A BLAST analysis was used to suggest cross-reactivity with RIG-1 with Human, Rat and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with RIG-1 from other sources has not been determined. RIG-1 antibody detects the human RIG-1 protein. The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKε through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus. Anti-RIG-1 antibodies are ideal for investigators involved in infectious disease research. |
| Immunogen | RIG-1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with human GST-tagged RIG-1 protein. |
| Other Names | Retinoic acid inducible gene 1 protein, RIG-I, Dead box protein 58, ddx58, Probable ATP-dependent RNA helicase DDX58, RIG-I-like receptor 1, RLR-1, RIG-1, Retinoic acid-inducible gene I protein |
| Gene, Accession # | DDX58, Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
| Catalog # | 600-401-H15 |
| Price | $475 |
| Order / More Info | RIG-1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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