p73 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-p73 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | p73 |
| Clone | 5B429 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-p73 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-p73 from Human and Mouse based on 100% homology with the immunizing sequence. It does not cross react with p53. Cross-reactivity with Anti-p73 from other sources has not been determined. Anti-p73 detects human p73. NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines initiates a signal transduction cascade that leads to the activation of IkB-kinase complex that specifically phosphorylates IkBa on Serine-32 and Serine-36. Phosphorylation of these sites leads to ubiquitination of IkBa and subsequent degradation by the 26 S proteasome. Degradation of IkBa results in unmasking of the nuclear localization signal of NF-kB dimers, which subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBa. Anti-p73 antibody is ideal for investigators involved in NFkappaB, kinase and Apoptosis research. |
| Immunogen | p73 Antibody was produced in mice prepared by repeated immunizations with full-length human p73 protein. |
| Other Names | P73, Tumor protein p73, p53-like transcription factor, p53-related protein |
| Gene, Accession # | TP73, Gene ID: 7161, NCBI: NP_001119712.1, UniProt: O15350 |
| Catalog # | 200-301-I00 |
| Price | $525 |
| Order / More Info | p73 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies