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Antigenic Specificity | CD80 |
Clone | 2D10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | phycoerythrin (RPE) conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phycoerythrin conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD80. Reactivity is observed against human CD80. Cross reactivity is observed with Rhesus. Reactivity with CD80 from other sources has not been tested. Anti-CD80 is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. |
Immunogen | Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen. |
Other Names | T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD28LG, CD28LG1, LAB7 |
Gene, Accession # | CD80, Gene ID: 941, NCBI: NP_005182.1, UniProt: P33681 |
Catalog # | 200-308-N74 |
Price | $495 |
Order / More Info | CD80 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |