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Antigenic Specificity | Myelin Basic Protein (MBP) |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat, bovine |
Isotype | n/a |
Format | IgY fraction |
Size | 100 µL |
Concentration | Titrated value sufficient to run approximately 10 mini blots. |
Applications | IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MBP antibody is directed against Myelin basic protein. The antibody is a total IgY fraction. The antibody has been directly tested for reactivity in bovine, human, mouse and rat tissues. Cross reactivity with MBP from other mammalian tissues is expected. Myelin Basic Protein antibody detects MBP. MBP is one of the major proteins of the myelin sheath surrounding axons in the nervous system. Since it is of relatively low molecular weight and high abundance the protein sequence was determined from purified protein over 30 years ago. The protein is made by oligodendrocytes in the central nervous system, so antibodies to MBP are good markers of this cell type. However, transcripts from the same gene are also expressed in certain hematopoetic lineage cells. In the central nervous system there are there different forms of the protein made by alternate transcription from a single gene, which have molecular weights of 21.5, 18.5, and 17.2 kDa. Since the two lower molecular weight forms are very close in molecular size, MBP antibodies typically show two bands on Western blots, one at about 22kDa and another at about 18kDa. Anti-MBP antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research. |
Immunogen | Anti-Myelin basic protein Antibody was produced in chicken by repeated immunizations with three peptide sequences conserved in higher vertebrate MBP proteins. |
Other Names | Myelin A1 protein, Myelin membrane encephalitogenic protein, Myelin basic protein, MBP, Myelin basic protein S, MBP S antibody |
Gene, Accession # | Mbp, Gene ID: 24547, NCBI: NP_001020465.1, UniProt: P02688 |
Catalog # | 200-901-D81 |
Price | $475 |
Order / More Info | Myelin Basic Protein (MBP) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |